SMTP Error Code 451

The mail server encountered a temporary failure. If the command is repeated without any change, it might be completed. Mail servers can use temporary failures like this to keep untrusted senders at bay.

Providers

Barracuda · Exchange Online · Google · Mimecast · Outlook.com · Rackspace · Yahoo · Yandex · Zoho · iCloud

Barracuda↑: 451 4.7.1 <email@example.com>: Recipient address rejected: Greylisted for 5 minutes; 451 4.7.1 Try again later; 451 cuda_nsu 4.4.3 Temporary server error. Please try again later
Exchange Online↑: 451 4.7.0 Temporary server error. Please try again later. PRX4 NextHop: example.com [example.com]; 451 4.7.500 Server busy. Please try again later from [x.xx.xx.x]. (AS77712344) [#.prod.protection.outlook.com]; 451 4.4.62 Mail sent to the wrong Office 365 region. ATTR35. For more information please go to https://go.microsoft.com/fwlink/?linkid=865268 [#.prod.protection.outlook.com]
This error can result from misconfigured connectors, expired certificates, or incorrect mail routing in hybrid Exchange environments.

https://learn.microsoft.com/en-us/exchange/troubleshoot/email-delivery/wrong-office-365-region-exo
Google↑: 451 4.3.0 Mail server temporarily rejected message. - gsmtp
The mail server encountered a temporary failure. Most likely it isn't anything to do with the session, but rather the server is overloaded or having issues. If you try again later, it should work.

https://support.google.com/mail/answer/81126
Mimecast↑: 451 Open relay not allowed
The sender and recipient domains specified in the transmission are external to Mimecast. They aren't allowed to relay through the Mimecast service, and/or the connecting IP address isn't recognized as authorized.

https://mimecastsupport.zendesk.com/hc/en-us/articles/34000709564691-Policies-Mimecast-SMTP-Error-Codes; 451 Internal resource temporarily unavailable
The sending mail server is subjected to Greylisting. This requires the server to retry the connection between one minute and 12 hours. Alternatively, the sender's IP address has a poor reputation.

https://mimecastsupport.zendesk.com/hc/en-us/articles/34000709564691-Policies-Mimecast-SMTP-Error-Codes; 451 Account inbounds disabled.
The customer account Inbound emails are disabled in the Mimecast Administration Console.

https://mimecastsupport.zendesk.com/hc/en-us/articles/34000709564691-Policies-Mimecast-SMTP-Error-Codes; 451 Account service is temporarily unavailable
There are too many concurrent inbound connections for the account. The default is 20.

https://mimecastsupport.zendesk.com/hc/en-us/articles/34000709564691-Policies-Mimecast-SMTP-Error-Codes
Outlook.com↑: 451 4.3.2 Temporary server error. Please try again later ATTR17 [outlook.com]
The mail server encountered a temporary failure. Most likely it isn't anything to do with the session, but rather the server is overloaded or having issues. If you try again later, it should work.; 451 4.4.0 Message failed to be replicated: No healthy secondary server available to accept replica at this time. [outlook.com]
The sender's domain is currently unable to accept this message. Sending email in the future will most likely be successful.; 451 4.7.0 Temporary server error. Please try again later. PRX6 NextHop: outlook.com [outlook.com]
The sender's domain is currently unable to accept this message. Sending email in the future will most likely be successful.; 451 4.7.650 The mail server [x.xx.xx.xx] has been temporarily rate limited due to IP reputation. For e-mail delivery information, see https://postmaster.live.com (S843)[#.prod.protection.outlook.com]
Outlook has determined that the sending IP address has a low reputation, so messages are now temporarily rejected. See Microsoft's documentation on how to determine the source of this poor reputation and how to improve deliverability.; 451 4.7.651 The mail server [x.xx.xx.xx] has been temporarily rate limited due to IP reputation. For e-mail delivery information, see https://postmaster.live.com (S3114) [#.prod.outlook.com #]
Outlook has determined that the sending IP address has a low reputation, so messages are now temporarily rejected. See Microsoft's documentation on how to determine the source of this poor reputation and how to improve deliverability.
Rackspace↑: 451 4.7.1 Received too many messages from a new or untrusted IP (G28)
Rackspace require that incoming IPs establish good sending behavior before sending large volumes of mail to their platform. Be sure to warm up your IP correctly with them and throttle your sending for the next couple of weeks.

https://postmaster.emailsrvr.com/system-info/response-codes
Yahoo↑: 451 example.yahoo.com Resources temporarily unavailable. Please try again later [#4.16.1].
The sender's domain is currently unable to accept this message. Sending email in the future will most likely be successful.

https://postmaster.yahooinc.com/error-codes; 451 4.3.2 Internal server error
The mail server encountered a temporary failure. Most likely it isn't anything to do with the session, but rather the server is overloaded or having issues. If you try again later, it should work.

https://postmaster.yahooinc.com/error-codes
Yandex↑: 451 4.7.1 Sorry, the service is currently unavailable. Please come back later.
Zoho↑: 541 5.4.1 Mail rejected by destination domain
Zoho allows the receiving domain to set mail filters. The receiving domain has filters set-up that are blocking this message. To resolve this, you'll need to contact an administrator of this domain through another channel to have them adjust their filters and allow delivery.
iCloud↑: 451 4.7.1 Service unavailable - try again later
Messages are not being accepted right now. You may usually see this for sends happening at the "top of the hour" when many senders around the world are also sending aggressively to Apple.

https://support.apple.com/en-us/HT204137